Biophotonics across Energy, Space and Time
Microscale Biophotonics: Microscopy and Microbeams
Microscopy and Microbeams

Optical microscopy and laser microbeams provide essential tools in molecular, cellular, and developmental biology, neuroscience, biophysics, and biotechnology. In fact it is difficult to imagine how progress in these fields could be made without the ability to selectively locate and quantify the concentration and dynamics of biomolecular and cellular constituents on nanoscopic and microscopic spatial scales.

UCI enjoys a strong tradition in the field of optical microscopy and focused laser microbeams, and BEST faculty members have pioneered many of the optical techniques that are now standard research tools in the biological sciences. Seminal advances made by BEST faculty span the development of state-of-the-art fluorescence correlation methods (Gratton), nonlinear optical imaging (Cahalan, Gratton, Parker, Potma, Tromberg), and laser microbeam technologies (Berns, Botvinick, Gross, Venugopalan) combined with their applications to investigate biological processes as well as to probe and manipulate cells and tissues on nanoscopic spatial and temporal scales.

These research efforts are established across Departmental lines, and have brought together the strengths of various research groups in Biomedical Engineering, Chemistry, Chemical Engineering & Materials Science, Developmental & Cell Biology, Neurobiology & Behavior, and Physiology & Biophysics. The interplay between biological need and technology development has benefitted from a constructive “push-pull” relationship.

BEST Faculty for Microscopy and Microbeams

Berns (Biomedical Engineering, Developmental & Cell Biology, Surgery), Botvinick (Biomedical Engineering, Surgery) Cahalan (Physiology & Biophysics), Gratton (Biomedical Engineering, Physics & Astronomy), Gross (Developmental & Cell Biology, Physics & Astronomy), Lander (Developmental & Cell Biology, Biomedical Engineering), Parker (Neurobiology & Behavior), Potma (Chemistry, Surgery), Tromberg (Biomedical Engineering, Surgery), Venugopalan (Chemical Engineering & Materials Science, Biomedical Engineering, Surgery)